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I manage the HPC cluster for a number of medical imaging research labs at Univ. of Penn, at the School of Medicine and other groups. So a small slice of the big pie, with currently about a half dozen regular X2Go users who (very succesfully!) use it to remotely access our compute cluster and ancillary servers. It really works very well, hats off to you and your team. Without X2Go, the performance of X11 apps is barely usable over remote VPN connection. Sometimes we also use it within the local university network to get better graphics performance. One user uses it via cellular from his laptop on the train during his commute, going through VPN, and gets good response for a 2D image analysis tool we use.